A polystyrene mouse cage

A Polystyrene Mouse Cage.

A robust automated system elucidates mouse home cage behavioral structure.

Patterns of behavior exhibited by mice in their home cages reflect the function and interaction of numerous behavioral and physiological systems. Detailed assessment of these patterns thus has the potential to provide a powerful tool for understanding basic aspects of behavioral regulation and their perturbation by disease processes. However, the capacity to identify and examine these patterns ...

Automated Operant Conditioning in the Mouse Home Cage

Recent advances in neuroimaging and genetics have made mice an advantageous animal model for studying the neurophysiology of sensation, cognition, and locomotion. A key benefit of mice is that they provide a large population of test subjects for behavioral screening. Reflex-based assays of hearing in mice, such as the widely used acoustic startle response, are less accurate than operant conditi...

FANTOM5 CAGE profiles of human and mouse samples

In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples, consisting of a variety of primary cells, tissues, cell lines, and time series samples during cell ...

A Polystyrene-Water Calorimeter

The paper describes a new type of calorimeter that can be quickly put into operation for determining absorbed dose at a point in polystyrene. It also describes a unique method of decreasing drifts in electrical signals caused by temperature gradients. Two calibrated thermistors were placed close together between sandwiched polystyrene discs that were immersed in water. The assembly was irradiat...